Peripapillary pachychoroid neovasculopathy: A novel entity.
Por:
Montero Hernández J, Remolí Sargues L, Monferrer Adsuara C, Castro Navarro V, Navarro Palop C, Cervera Taulet E
Ahead of Print:
25 ago 2020
Resumen:
PURPOSE: Peripapillary pachychoroid syndrome is a new variant of pachychoroid disease recently described. It is important to establish the features and pathogenic mechanisms of this novel entity and its possible association with type 1 neovascularization. The aim of this study is to report a case of peripapillary pachychoroid neovasculopathy, a novel entity of pachychoroid spectrum disease. CASE REPORT: A 51-year-old woman was referred to our macula service due to macular pigmentary changes in her right eye. On examination, best corrected visual acuity was 20/20 Snellen equivalent in both eyes. Funduscopy revealed pigmentary changes in the papillonasal bundle in her right eye with mottled autofluorescence in the same area where pigmentary changes. Spectral-domain optical coherence tomography illustrated a shallow irregular pigment epithelium detachment (PED) which appears as "double layer sign" overlying pachyvessels, with hyper-flow signal beneath it and a large network of neovascularization revealed by cross-sectional optical coherence tomography angiography. Indocyanine green angiography confirmed the pachyvessels and choroidal hyper-permeability in the peripapillary region. A diagnosis of peripapillary pachychoroid neovasculopathy was made and good visual and anatomical outcomes were achieved with a treat-and-extend regimen with intravitreal aflibercept. CONCLUSION: We report a novel entity within the pachychoroid spectrum disease, the peripapillary pachychoroid neovasculopathy, which could improve our understanding of the pathogenic mechanism of choroidal neovascularization in pachychoroid disorders.
Filiaciones:
Montero Hernández J:
Department of Ophthalmology, Consorcio Hospital General Universitario of Valencia, Valencia, Spain
Remolí Sargues L:
Department of Ophthalmology, Consorcio Hospital General Universitario of Valencia, Valencia, Spain
Monferrer Adsuara C:
Department of Ophthalmology, Consorcio Hospital General Universitario of Valencia, Valencia, Spain
Castro Navarro V:
Department of Ophthalmology, Consorcio Hospital General Universitario of Valencia, Valencia, Spain
Navarro Palop C:
Department of Ophthalmology, Consorcio Hospital General Universitario of Valencia, Valencia, Spain
Cervera Taulet E:
Department of Ophthalmology, Consorcio Hospital General Universitario of Valencia, Valencia, Spain
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