Obesity and Cardiometabolic Risk Factors: From Childhood to Adulthood
Por:
Drozdz, D, Alvarez-Pitti, J, Wojcik, M, Borghi, C, Gabbianelli, R, Mazur, A, Herceg-Cavrak, V, Lopez-Valcarcel, BG, Brzezinski, M, Lurbe, E, Wuehl, E
Publicada:
1 nov 2021
Resumen:
Obesity has become a major epidemic in the 21st century. It increases the risk of dyslipidemia, hypertension, and type 2 diabetes, which are known cardiometabolic risk factors and components of the metabolic syndrome. Although overt cardiovascular (CV) diseases such as stroke or myocardial infarction are the domain of adulthood, it is evident that the CV continuum begins very early in life. Recognition of risk factors and early stages of CV damage, at a time when these processes are still reversible, and the development of prevention strategies are major pillars in reducing CV morbidity and mortality in the general population. In this review, we will discuss the role of well-known but also novel risk factors linking obesity and increased CV risk from prenatal age to adulthood, including the role of perinatal factors, diet, nutrigenomics, and nutri-epigenetics, hyperuricemia, dyslipidemia, hypertension, and cardiorespiratory fitness. The importance of 'tracking' of these risk factors on adult CV health is highlighted and the economic impact of childhood obesity as well as preventive strategies are discussed.
Filiaciones:
Drozdz, D:
Jagiellonian Univ Med Coll, Pediat Inst, Dept Pediat Nephrol & Hypertens, PL-30663 Krakow, Poland
Alvarez-Pitti, J:
Univ Valencia, Consorcio Hosp Gen, Pediat Dept, Valencia 46014, Spain
Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain
Univ Valencia, Hosp Clin, INCL Biomed Res Inst, Valencia 46010, Spain
Wojcik, M:
Jagiellonian Univ Med Coll, Pediat Inst, Dept Pediat & Adolescent Endocrinol, PL-30663 Krakow, Poland
Borghi, C:
Univ Bologna IRCCS S Orsola, Dept Med & Surg Sci, I-40126 Bologna, Italy
Gabbianelli, R:
Univ Camerino, Sch Pharm, Unit Mol Biol & Nutrigen, I-62032 Camerino, Italy
Mazur, A:
Univ Rzeszow, Med Fac, Dept Pediat Pediat Endocrinol & Diabet, PL-35310 Rzeszow, Poland
Herceg-Cavrak, V:
Libertas Int Univ, Childrens Hosp Zagreb, Zagreb 10000, Croatia
Lopez-Valcarcel, BG:
Univ Las Palmas Gran Canaria, Dept Quantitat Methods Econ & Management, Las Palmas Gran Canaria 35017, Spain
Brzezinski, M:
Med Univ Gdansk, Dept Pediat Gastroenterol Allergol & Pediat Nutr, PL-80210 Gdansk, Poland
Lurbe, E:
Univ Valencia, Consorcio Hosp Gen, Pediat Dept, Valencia 46014, Spain
Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain
Univ Valencia, Hosp Clin, INCL Biomed Res Inst, Valencia 46010, Spain
Wuehl, E:
Heidelberg Univ Hosp, Ctr Pediat & Adolescent Med, Div Pediat Nephrol, D-69120 Heidelberg, Germany
Green Published, gold
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